Gynecomastia is a benign enlargement of the male breast tissue, either due to the proliferation of glandular tissue or deposition Accessories of fat in breast tissue, usually caused by imbalance of estrogen and androgen hormones in body.Gynecomastia has a trimodal age distribution and begins as a small lump beneath the nipple which may be tender.Gy
Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs), but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear.To address this question, we generated new mouse models with ablation of Col2+ cells at either the embryonic or postnatal st
Cells generate diverse microtubule populations by polymerization of a common alpha/beta-tubulin building block.How microtubule associated proteins translate microtubule heterogeneity into specific cellular functions is not clear.We evaluated the ability of kinesin motors involved in vesicle transport to read microtubule heterogeneity by using singl
Abstract Background Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle.Origin choice is linked to cell growth, differentiation, and replication stress.Although various genetic and epigenetic signatures have been linked to the replication efficiency of origins, there i